The research in our Lab is focused on: (1) Design, synthesis and development of novel small-molecule drugs and multitarget inhibitors to treat human diseases including cancer (e.g. breast cancer), metabolic diseases (e.g. type II diabetes) and neurological diseases (e.g. Alzheimer’s disease (AD)) using medicinal chemistry strategies in association with computer-aided rational drug design. (2) Application of new computational and informatics methods and tools for drug design and discovery. (3) Development of novel organic synthetic methodologies to achieve efficient drug synthesis and diversity-oriented synthesis.
